Although Acremonium strictum is environmentally widespread as opportunistic mold, it may
cause infection in patients who have immunodeficiency problems. In this study,
Staphylococcus aureus and A. strictum were isolated from the pleural fluid of a patient with
colon adenocarcinoma. The patient did not receive antifungal therapy because the patient
died after the isolation of mold. The minimal inhibitory concentrations of amphotericin B,
fluconazole, ketoconazole, itraconazole, voriconazole for the A. strictum strain isolated from …

A 23-year-old boy was hospitalized for dyspnea with mild fever. Chest x-ray documented left
pleural effusion. Cultures from thoracentesis grew out Acremonium strictum and intravenous
liposomal amphotericin B was given at a dose of 200 mg daily. On treatment, fever subsided
but dyspnea worsened. Whole-body CT scan showed multiple bilateral lung nodules,
systemic lymphadenopathies and a mass over the left testis. Biopsies from an enlarged
supraclavicular lymph node revealed metastatic testicular teratocarcinoma. Chemotherapy …